cgp 39551 Search Results


anticonvulsant compound cgp 39551  (Tocris)
94
Tocris anticonvulsant compound cgp 39551
Anticonvulsant Compound Cgp 39551, supplied by Tocris, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anticonvulsant compound cgp 39551/product/Tocris
Average 94 stars, based on 1 article reviews
anticonvulsant compound cgp 39551 - by Bioz Stars, 2026-05
94/100 stars
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cgp39551  (Tocris)
92
Tocris cgp39551
a , d , g , Chemical structure of <t>CGP39551,</t> CPP and L-Aminoadipic acid (L-AA). b , c , e , f , 100 μM CGP39551 and CPP, competitive antagonists of NMDA receptors, had no effect on I ASICs and could not block glutamate-induced potentiation of I ASICs . n = 9 cells ( b ), 9 cells ( c ), 13 cells ( e ) and 14 cells ( f ). h , i , 100 μM L-AA, an agonist for NMDAR and metabotropic glutamate receptors (mGluRs), had no effect on I ASICs , however, could eliminate glutamate-induced potentiation of I ASICs . n = 13 cells ( h ) and 13 cells ( i ). Three to six replicated cultures for patch recordings were tested. Data are mean±s.e.m.; two-tailed paired t -test ( b , e , h ); one-way ANOVA with Tukey post hoc correction ( c , f , i ). P values are indicated.
Cgp39551, supplied by Tocris, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cgp39551/product/Tocris
Average 92 stars, based on 1 article reviews
cgp39551 - by Bioz Stars, 2026-05
92/100 stars
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cgp 39551  (Ciba Geigy)
90
Ciba Geigy cgp 39551
a , d , g , Chemical structure of <t>CGP39551,</t> CPP and L-Aminoadipic acid (L-AA). b , c , e , f , 100 μM CGP39551 and CPP, competitive antagonists of NMDA receptors, had no effect on I ASICs and could not block glutamate-induced potentiation of I ASICs . n = 9 cells ( b ), 9 cells ( c ), 13 cells ( e ) and 14 cells ( f ). h , i , 100 μM L-AA, an agonist for NMDAR and metabotropic glutamate receptors (mGluRs), had no effect on I ASICs , however, could eliminate glutamate-induced potentiation of I ASICs . n = 13 cells ( h ) and 13 cells ( i ). Three to six replicated cultures for patch recordings were tested. Data are mean±s.e.m.; two-tailed paired t -test ( b , e , h ); one-way ANOVA with Tukey post hoc correction ( c , f , i ). P values are indicated.
Cgp 39551, supplied by Ciba Geigy, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cgp 39551/product/Ciba Geigy
Average 90 stars, based on 1 article reviews
cgp 39551 - by Bioz Stars, 2026-05
90/100 stars
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cgp 39551  (Federation of European Neuroscience Societies)
90
Federation of European Neuroscience Societies cgp 39551
a , d , g , Chemical structure of <t>CGP39551,</t> CPP and L-Aminoadipic acid (L-AA). b , c , e , f , 100 μM CGP39551 and CPP, competitive antagonists of NMDA receptors, had no effect on I ASICs and could not block glutamate-induced potentiation of I ASICs . n = 9 cells ( b ), 9 cells ( c ), 13 cells ( e ) and 14 cells ( f ). h , i , 100 μM L-AA, an agonist for NMDAR and metabotropic glutamate receptors (mGluRs), had no effect on I ASICs , however, could eliminate glutamate-induced potentiation of I ASICs . n = 13 cells ( h ) and 13 cells ( i ). Three to six replicated cultures for patch recordings were tested. Data are mean±s.e.m.; two-tailed paired t -test ( b , e , h ); one-way ANOVA with Tukey post hoc correction ( c , f , i ). P values are indicated.
Cgp 39551, supplied by Federation of European Neuroscience Societies, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cgp 39551/product/Federation of European Neuroscience Societies
Average 90 stars, based on 1 article reviews
cgp 39551 - by Bioz Stars, 2026-05
90/100 stars
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cgp 39551  (Aladdin Scientific Corporation)
N/A
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
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cgp 39551  (Santa Cruz Biotechnology)
N/A
CGP 39551 is a potent, selective, and competitive NMDA antagonist.
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cgp 39551  (BOC Sciences)
N/A
Cgp 39551 is a selective and competitive N-methyl-D-aspartate (NMDA) receptor antagonist originated by Novartis. Ki is 310 nM for inhibition of [3H]-CPP binding in rat brain. CGP 39551 produces excitatory effects and causes psychotomimetic effects
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cgp 39551  (Biosynth Carbosynth)
N/A
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cgp 39551  (TargetMol)
N/A
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Image Search Results


a , d , g , Chemical structure of CGP39551, CPP and L-Aminoadipic acid (L-AA). b , c , e , f , 100 μM CGP39551 and CPP, competitive antagonists of NMDA receptors, had no effect on I ASICs and could not block glutamate-induced potentiation of I ASICs . n = 9 cells ( b ), 9 cells ( c ), 13 cells ( e ) and 14 cells ( f ). h , i , 100 μM L-AA, an agonist for NMDAR and metabotropic glutamate receptors (mGluRs), had no effect on I ASICs , however, could eliminate glutamate-induced potentiation of I ASICs . n = 13 cells ( h ) and 13 cells ( i ). Three to six replicated cultures for patch recordings were tested. Data are mean±s.e.m.; two-tailed paired t -test ( b , e , h ); one-way ANOVA with Tukey post hoc correction ( c , f , i ). P values are indicated.

Journal: Nature

Article Title: Glutamate acts on acid-sensing ion channels to worsen ischaemic brain injury

doi: 10.1038/s41586-024-07684-7

Figure Lengend Snippet: a , d , g , Chemical structure of CGP39551, CPP and L-Aminoadipic acid (L-AA). b , c , e , f , 100 μM CGP39551 and CPP, competitive antagonists of NMDA receptors, had no effect on I ASICs and could not block glutamate-induced potentiation of I ASICs . n = 9 cells ( b ), 9 cells ( c ), 13 cells ( e ) and 14 cells ( f ). h , i , 100 μM L-AA, an agonist for NMDAR and metabotropic glutamate receptors (mGluRs), had no effect on I ASICs , however, could eliminate glutamate-induced potentiation of I ASICs . n = 13 cells ( h ) and 13 cells ( i ). Three to six replicated cultures for patch recordings were tested. Data are mean±s.e.m.; two-tailed paired t -test ( b , e , h ); one-way ANOVA with Tukey post hoc correction ( c , f , i ). P values are indicated.

Article Snippet: All experiments were performed at room temperature (21–26 °C). d -AP5, CGS19755, amiloride and PcTX-1 were purchased from Alomone Labs; l -AP5 and CGP39551 were purchased from Tocris; NBQX, LY341495, CGP37157 and RO2959 were purchased from MedChemExpress; and other chemicals were purchased from Sigma-Aldrich or Macklin.

Techniques: Blocking Assay, Two Tailed Test